Chlormidazole

Chemical compound

Identifiers

CAS Number

PubChem CID

ChemSpider

UNII

KEGG

ChEMBL

CompTox Dashboard (EPA)

ECHA InfoCard100.020.908

Chemical and physical dataFormulaC₁₅H₁₃ClN₂Molar mass256.73 g·mol⁻¹3D model (JSmol)

Chlormidazole (INN, also known as clomidazole) is used as a spasmolytic and azole antifungal drug.^[1]

Synthesis

^ Krasiejko I, Gajewicz L, Lipnicki D (1990). "[Sensitivity of aerobic bacteria and Candida species to chlormidazole hydrochloride in vitro]". Polski Tygodnik Lekarski (in Polish). 45 (4–5): 91–2. PMID 2395759.

Wall/
membrane

Ergosterol
inhibitors

Azoles (lanosterol 14α-
demethylase inhibitors)

Imidazoles	Topical: bifonazole^‡ butoconazole chlormidazole^‡ climbazole clotrimazole^# croconazole^‡ eberconazole econazole fenticonazole^‡ flutrimazole isoconazole ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole
Triazoles	Topical: efinaconazole fluconazole^# terconazole Systemic: fluconazole^# fosfluconazole fosravuconazole hexaconazole^‡ isavuconazole itraconazole^# oteseconazole posaconazole voriconazole^# Unknown: albaconazole^‡ ravuconazole^†
Thiazoles	Topical: abafungin^‡

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine
Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	Systemic: flucytosine^#
Mitotic inhibitors	Systemic: griseofulvin^#
Aminoacyl tRNA synthetase inhibitors	Topical: tavaborole