EHNA

Chemical compound

EHNA
Identifiers

IUPAC name 3-(6-aminopurin-9-yl)nonan-2-ol
CAS Number	59262-86-1
PubChem CID	3206
ChemSpider	3094
ChEMBL	ChEMBL50378^Y
CompTox Dashboard (EPA)	DTXSID70110044
Chemical and physical data
Formula	C₁₄H₂₃N₅O
Molar mass	277.372 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCCCCCC(C(C)O)n1cnc2c1ncnc2N
InChI InChI=1S/C14H23N5O/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17) Key:IOSAAWHGJUZBOG-UHFFFAOYSA-N
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EHNA (erythro-9-(2-hydroxy-3-nonly)adenine) is a potent adenosine deaminase inhibitor,^[1] which also acts as a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type 2 (PDE2).^[2]^[3]

References

^ "Sigma Aldrich". Retrieved 16 January 2013.
^ Podzuweit T, Nennstiel P, Müller A (September 1995). "Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine". Cellular Signalling. 7 (7): 733–8. doi:10.1016/0898-6568(95)00042-N. PMID 8519602.
^ Méry PF, Pavoine C, Pecker F, Fischmeister R (July 1995). "Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes". Molecular Pharmacology. 48 (1): 121–30. PMID 7623766.