KIF24

Protein-coding gene in the species Homo sapiens
KIF24
Identifiers
AliasesKIF24, C9orf48, bA571F15.4, kinesin family member 24
External IDsOMIM: 613747; MGI: 1918345; HomoloGene: 52346; GeneCards: KIF24; OMA:KIF24 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for KIF24
Genomic location for KIF24
Band9p13.3Start34,252,380 bp[1]
End34,329,268 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for KIF24
Genomic location for KIF24
Band4|4 A5Start41,390,745 bp[2]
End41,464,887 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad

  • ventricular zone

  • testicle

  • right testis

  • left testis

  • right uterine tube

  • ganglionic eminence

  • stromal cell of endometrium

  • olfactory zone of nasal mucosa

  • bone marrow cells
Top expressed in
  • morula

  • lumbar subsegment of spinal cord

  • zygote

  • hand

  • secondary oocyte

  • spermatocyte

  • tail of embryo

  • primary oocyte

  • genital tubercle

  • spermatid
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • microtubule binding
  • microtubule motor activity
  • nucleotide binding
  • ATPase activity
  • protein binding
  • ATP binding
  • identical protein binding
Cellular component
  • cytoplasm
  • centriole
  • cytosol
  • microtubule
  • cytoskeleton
  • kinesin complex
  • protein-containing complex
Biological process
  • microtubule-based movement
  • microtubule depolymerization
  • cell projection organization
  • cilium assembly
  • ciliary basal body-plasma membrane docking
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

347240

109242

Ensembl

ENSG00000186638

ENSMUSG00000028438

UniProt

Q5T7B8

Q6NWW5

RefSeq (mRNA)

NM_194313

NM_024241
NM_145101

RefSeq (protein)

NP_919289

NP_077203

Location (UCSC)Chr 9: 34.25 – 34.33 MbChr 4: 41.39 – 41.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin-like protein KIF24 is a protein that in humans is encoded by the KIF24 gene.[5][6] It is part of the kinesin family of motor proteins.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186638 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028438 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: C9orf48 chromosome 9 open reading frame 48".

Further reading

  • Miki H, Setou M, Kaneshiro K, Hirokawa N (2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7004–11. Bibcode:2001PNAS...98.7004M. doi:10.1073/pnas.111145398. PMC 34614. PMID 11416179.
  • Tsuritani K, Irie T, Yamashita R, et al. (2007). "Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes". Genome Res. 17 (7): 1005–14. doi:10.1101/gr.6030107. PMC 1899111. PMID 17567985.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.


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