RTRAF

Protein-coding gene in the species Homo sapiens
RTRAF
Identifiers
AliasesRTRAF, CGI99, CLE, CLE7, LCRP369, RLLM1, CGI-99, C14orf166, hCLE1, chromosome 14 open reading frame 166, RNA transcription, translation and transport factor, hCLE
External IDsOMIM: 610858; MGI: 1915295; HomoloGene: 9355; GeneCards: RTRAF; OMA:RTRAF - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for RTRAF
Genomic location for RTRAF
Band14q22.1Start51,989,514 bp[1]
End52,010,694 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for RTRAF
Genomic location for RTRAF
Band14|14 A3Start19,861,419 bp[2]
End19,873,892 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • gonad

  • right testis

  • left testis

  • cartilage tissue

  • ganglionic eminence

  • Achilles tendon

  • palpebral conjunctiva

  • right ventricle

  • body of pancreas
Top expressed in
  • fossa

  • condyle

  • medial ganglionic eminence

  • endothelial cell of lymphatic vessel

  • trigeminal ganglion

  • primitive streak

  • renal corpuscle

  • vestibular sensory epithelium

  • medullary collecting duct

  • vas deferens
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • RNA polymerase II complex binding
  • identical protein binding
  • RNA binding
  • protein binding
Cellular component
  • cytoskeleton
  • cytosol
  • nucleus
  • tRNA-splicing ligase complex
  • cytoplasm
  • microtubule organizing center
  • nucleoplasm
  • centrosome
  • perinuclear region of cytoplasm
  • mitotic spindle
Biological process
  • RNA transport
  • regulation of transcription, DNA-templated
  • positive regulation of transcription by RNA polymerase II
  • transcription, DNA-templated
  • viral process
  • tRNA splicing, via endonucleolytic cleavage and ligation
  • negative regulation of protein kinase activity
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51637

68045

Ensembl

ENSG00000087302

ENSMUSG00000021807

UniProt

Q9Y224

Q9CQE8

RefSeq (mRNA)

NM_016039

NM_026528

RefSeq (protein)

NP_057123

NP_080804

Location (UCSC)Chr 14: 51.99 – 52.01 MbChr 14: 19.86 – 19.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA transcription, translation and transport factor is a protein that in humans is encoded by the RTRAF gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000087302 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021807 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  6. ^ "RTRAF RNA transcription, translation and transport factor [ Homo sapiens (human) ]". Retrieved 2019-04-28.

Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Howng SL, Hsu HC, Cheng TS, et al. (2004). "A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors". FEBS Lett. 566 (1–3): 162–8. doi:10.1016/j.febslet.2004.04.024. PMID 15147888.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Huarte M, Sanz-Ezquerro JJ, Roncal F, et al. (2001). "PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators". J. Virol. 75 (18): 8597–604. doi:10.1128/JVI.75.18.8597-8604.2001. PMC 115105. PMID 11507205.
  • Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.


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