Thiazide-like diuretic

A thiazide-like diuretic is a sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but does not have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure. Examples include metolazone, chlorthalidone, and indapamide.[1]

References

  1. ^ Foye's Principles of Medicinal Chemistry. David Williams (ed.) (7th ed.). Philadelphia: LWW. 2012-03-16. ISBN 978-1-60913-345-0.{{cite book}}: CS1 maint: others (link)
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Diuretics (C03)
Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
  • Acetazolamide
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)Vasopressin receptor inhibitors
(DCT and CD)OtherCombination products


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