| An | Titlu | Platformă | Dezvoltator, editor |
| 1971 | Star Trek (text game) | multiple | Mike Mayfield |
| 1972 | Star Trek (script game) | PDP-10 | Don Daglow |
| 1979 | Apple Trek | Apple II | |
| 1980 c. | 3-D Star Trek | Atari 800 | Color Software |
| 1980 | Star Trek 3.5 | TRS-80, Apple II, Atari 800 | Adventure International |
| 1981 | Tari Trek | Atari 800 | Quality Software |
| 1981 | Begin: A Tactical Starship Simulation | DOS | |
| 1982 | The Warp Factor | Apple II, DOS | Strategic Simulations, Inc. |
| 1983 | Star Trek: Strategic Operations Simulator (ports) | VIC-20 | |
| 1984 | Star Trek: The Promethean Prophecy | Apple II, C64, DOS | Simon & Schuster |
| 1985 | Star Trek: The Kobayashi Alternative | Apple II, C64, DOS | Simon & Schuster |
| 1987 | Star Trek: The Rebel Universe | Atari ST, C64, DOS | Simon & Schuster |
| 1988 | Star Trek: First Contact | DOS | |
| 1989 | Star Trek: The Next Generation: The Transinium Challenge | DOS | |
| 1989 | Star Trek V: The Final Frontier | DOS | |
| 1991 | Begin 2 (game) | DOS | |
| 1992 | Star Trek: 25th Anniversary | DOS, Macintosh, Amiga | Interplay Entertainment |
| 1993 | Star Trek: Judgment Rites | DOS, Macintosh | Interplay Entertainment |
| 1995 | Star Trek: The Next Generation - A Final Unity | DOS, Macintosh | Spectrum HoloByte, MicroProse |
| 1995 | Star Trek: Klingon | Windows | Simon & Schuster |
| 1996 | Star Trek: Borg | Windows, Macintosh | Simon & Schuster |
| 1996 | Star Trek: Deep Space Nine: Harbinger | DOS, Macintosh | Stormfront Studios, Viacom NewMedia |
| 1997 | Star Trek: Starfleet Academy | Windows, Macintosh | High Voltage Software, Interplay Entertainment |
| 1997 | Star Trek Generations | Windows | Microprose |
| 1997 | Star Trek Pinball | Windows | |
| 1998 | Star Trek: The Next Generation: Klingon Honor Guard | Windows, Macintosh | Microprose |
| 1998 | Star Trek: The Game Show | Windows, Macintosh | |
| 1998 | Star Trek: Starship Creator | Windows, Macintosh | Imergy, Simon & Schuster |
| 1999 | Star Trek: Birth of the Federation | Windows | Microprose, Hasbro |
| 1999 | Star Trek: Secret of Vulcan Fury | cancelled | Interplay Entertainment |
| 1999 | Star Trek: Starfleet Command | Windows | Quicksilver Software, Interplay Entertainment |
| 1999 | Star Trek: Hidden Evil | Windows | Presto Studios, Activision |
| 2000 | Star Trek: Armada | Windows | Mad Doc Software, Activision |
| 2000 | Star Trek: Deep Space Nine: The Fallen | Windows, Macintosh | The Collective, Inc., Simon & Schuster |
| 2000 | Star Trek: ConQuest Online | Windows | Genetic Anomalies, Activision |
| 2000 | Star Trek: Klingon Academy | Windows, Macintosh | 14 Degrees East, Interplay Entertainment |
| 2000 | Star Trek: New Worlds | Windows | 14 Degrees East, Interplay Entertainment |
| 2000 | Star Trek: Starship Creator Warp II | Windows | |
| 2000 | Star Trek: Voyager: Elite Force | Windows, Macintosh | Raven Software, Activision |
| 2001 | Star Trek: Deep Space Nine: Dominion Wars | Windows | Gizmo Games, Simon & Schuster |
| 2001 | Star Trek: Armada II | Windows | Mad Doc Software, Activision |
| 2001 | Star Trek: Away Team | Windows | Reflexive Entertainment, Activision |
| 2001 | Star Trek: Borg Assimilator | cancelled | Activision |
| 2001 | Star Trek: Starfleet Command II: Empires at War | Windows | Taldren, Interplay Entertainment |
| 2001 | Star Trek: Starfleet Command: Orion Pirates | Windows | Taldren, Interplay Entertainment |
| 2002 | Star Trek: Starfleet Command III | Windows | Taldren, Activision |
| 2002 | Star Trek: Bridge Commander | Windows | Totally Games, Activision |
| 2003 | Star Trek: Elite Force II | Windows, Macintosh | Ritual Entertainment, Activision |
| 2006 | Star Trek: Legacy | Windows, Xbox 360 | Mad Doc Software, Bethesda Softworks |
| 2009 | Star Trek: D-A-C | Windows, Xbox 360, Macintosh, PlayStation 3 | Naked Sky Entertainment, Paramount Digital Entertainment |
| 2010 | Star Trek Online | Windows | Cryptic Studios, Perfect World Entertainment |
| 2011 | Star Trek Infinite Space | Windows | GameForge |
| 2013 | Star Trek | Windows, Xbox 360, PlayStation 3 | Digital Extremes |
| 2016 | Star Trek Timelines | Browser, IOS, Android | Disruptor Beam |
