Meptazinol : Osobine, Reference, Literatura, Spoljašnje veze Википедија

Meptazinol

Meptazinol
Klinički podaci

Drugs.com	Monografija
Identifikatori
CAS broj	54340-58-8^Y
ATC kod	N02AX05 (WHO)
PubChem	CID 41049
ChemSpider	37469^Y
UNII	18Y7S5JKZD^Y
KEGG	D08182^Y
ChEMBL	CHEMBL314437^Y
Hemijski podaci
Formula	C₁₅H₂₃NO
Molarna masa	233,349
SMILES CCC1(CCCCN(C)C1)c2cccc(O)c2
InChI InChI=1S/C15H23NO/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13/h6-8,11,17H,3-5,9-10,12H2,1-2H3^Y Key:JLICHNCFTLFZJN-UHFFFAOYSA-N^Y

Meptazinol je organsko jedinjenje, koje sadrži 15 atoma ugljenika i ima molekulsku masu od 233,349 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	2
Broj donora vodonika	1
Broj rotacionih veza	2
Particioni koeficijent^[1] (ALogP)	3,5
Rastvorljivost^[2] (logS, log(mol/L))	-3,7
Polarna površina^[3] (PSA, Å²)	23,5

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.