SSBP2
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| Protein 2 vezivanja jednolančane DNK | |||||||||||
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| Identifikatori | |||||||||||
| Simboli | SSBP2; HSPC116; SOSS-B2 | ||||||||||
| Vanjski ID | OMIM: 607389 MGI: 1914220 HomoloGene: 22724 GeneCards: SSBP2 Gene | ||||||||||
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| Pregled RNK izražavanja | |||||||||||
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| Ortolozi | |||||||||||
| Vrsta | Čovek | Miš | |||||||||
| Entrez | 23635 | 66970 | |||||||||
| Ensembl | ENSG00000145687 | ENSMUSG00000003992 | |||||||||
| UniProt | P81877 | Q9CYZ8 | |||||||||
| Ref. Sekv. (iRNK) | NM_001256732 | NM_024186 | |||||||||
| Ref. Sekv. (protein) | NP_001243661 | NP_077148 | |||||||||
| Lokacija (UCSC) | Chr 5: 80.71 - 81.05 Mb | Chr 13: 91.46 - 91.7 Mb | |||||||||
| PubMed pretraga | [1] | [2] | |||||||||
Protein 2 vezivanja jednolančane DNK je protein koji je kod ljudi kodiran SSBP2 genom.[1][2][3]
Reference
- ↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). „Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs”. Genome Res 11 (3): 422–35. DOI:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- ↑ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). „Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells”. Genome Res 10 (10): 1546–60. DOI:10.1101/gr.140200. PMC 310934. PMID 11042152.
- ↑ „Entrez Gene: SSBP2 single-stranded DNA binding protein 2”.
Literatura
- Hu RM, Han ZG, Song HD, et al. (2000). „Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning”. Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. DOI:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001). „Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing”. EMBO Rep. 1 (3): 287–92. DOI:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Castro P, Liang H, Liang JC, Nagarajan L (2003). „A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity”. Genomics 80 (1): 78–85. DOI:10.1006/geno.2002.6805. PMID 12079286.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Liang H, Samanta S, Nagarajan L (2005). „SSBP2, a candidate tumor suppressor gene, induces growth arrest and differentiation of myeloid leukemia cells”. Oncogene 24 (16): 2625–34. DOI:10.1038/sj.onc.1208167. PMID 15782145.
- Rual JF, Venkatesan K, Hao T, et al. (2005). „Towards a proteome-scale map of the human protein-protein interaction network”. Nature 437 (7062): 1173–8. DOI:10.1038/nature04209. PMID 16189514.
- Fleisig HB, Orazio NI, Liang H, et al. (2007). „Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes”. Oncogene 26 (33): 4797–805. DOI:10.1038/sj.onc.1210281. PMID 17311003.
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i inicijacija
Prokariotska (inicijacija) | |
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Eukariotska (priprema u G1 fazi) | Prereplikacioni kompleks: Kompleks prepoznavanja mesta početka (ORC1, ORC2, ORC3, ORC4, ORC5, ORC6) • Održavanje minihromozoma (MCM2 • MCM3 • MCM4 • MCM5 • MCM6 • MCM7) • CDC6 Autonomna replikaciona sekvenca Protein jednolančanog vezivanja (SSBP1, SSBP2, SSBP3) Primaza: PRIM1 • PRIM2 |
Oba | Početak replikacije/Ori/Replikon Replikaciona viljuška (zaostajući i vodeći lanci) • Okazakijev fragment • Prajmer |
Prokariotska (elongacija) | DNK polimeraza III holoenzim (dnaC, dnaE, dnaH, dnaN, dnaQ, dnaT, dnaX, holA, holB, holC, holD, holE) • Replizom • DNK ligaza • DNK stega • Topoizomeraza (DNK giraza) Prokariotska DNK polimeraza: DNK polimeraza I (Klenov fragment) |
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Eukariotska (sinteza u S fazi) | |
Oba |
B bsyn: dnk (repl, cycl, reco, repr) • tscr (fact, tcrg, nucl, rnat, rept, ptts) • tltn (risu, pttl, nexn) • dnab, rnab/runp • stru (domn, 1°, 2°, 3°, 4°)
