CD300A |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | CD300A, CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60, CD300a molecule |
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External IDs | OMIM: 606790; MGI: 2443411; HomoloGene: 48514; GeneCards: CD300A; OMA:CD300A - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17q25.1 | Start | 74,466,399 bp[1] |
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End | 74,484,794 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - granulocyte
- blood
- monocyte
- spleen
- bone marrow
- bone marrow cells
- amniotic fluid
- appendix
- periodontal fiber
- lymph node
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| | More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - signaling receptor activity
- phosphatidylethanolamine binding
- phosphatidylserine binding
- protein binding
| Cellular component | - integral component of membrane
- extracellular exosome
- membrane
- plasma membrane
- tertiary granule membrane
- ficolin-1-rich granule membrane
| Biological process | - regulation of T cell receptor signaling pathway
- immune system process
- negative regulation of eosinophil migration
- positive regulation of phosphoprotein phosphatase activity
- negative regulation of neutrophil activation
- negative regulation of eosinophil activation
- regulation of immune response
- negative regulation of fibroblast proliferation
- negative regulation of MAP kinase activity
- negative regulation of mast cell degranulation
- negative regulation of mast cell activation involved in immune response
- cell adhesion
- negative regulation of NK T cell activation
- negative regulation of B cell receptor signaling pathway
- negative regulation of activation of Janus kinase activity
- negative regulation of phagocytosis, engulfment
- negative regulation of B cell proliferation
- signal transduction
- negative regulation of MyD88-dependent toll-like receptor signaling pathway
- neutrophil degranulation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001256841 NM_007261 NM_001330456 NM_001330457 |
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NM_170758 NM_001347654 NM_001359812 |
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RefSeq (protein) | |
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NP_001243770 NP_001317385 NP_001317386 NP_009192 |
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NP_001334583 NP_739564 NP_001346741 |
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Location (UCSC) | Chr 17: 74.47 – 74.48 Mb | n/a |
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PubMed search | [2] | [3] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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