PHF1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2E5P, 2M0O, 4HCZ |
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Identifiers |
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Aliases | PHF1, MTF2L2, PCL1, PHF2, TDRD19C, hPHD finger protein 1 |
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External IDs | OMIM: 602881 MGI: 98647 HomoloGene: 7567 GeneCards: PHF1 |
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Gene location (Human) |
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| Chr. | Chromosome 6 (human)[1] |
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| Band | 6p21.32 | Start | 33,410,399 bp[1] |
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End | 33,416,453 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17 A3.3|17 13.6 cM | Start | 27,152,026 bp[2] |
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End | 27,156,882 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - pituitary gland
- anterior pituitary
- left lobe of thyroid gland
- right lobe of thyroid gland
- canal of the cervix
- gastric mucosa
- popliteal artery
- prostate
- fundus
- hypothalamus
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| Top expressed in | - spermatocyte
- secondary oocyte
- spermatid
- ankle joint
- seminiferous tubule
- entorhinal cortex
- superior frontal gyrus
- islet of Langerhans
- cerebellar cortex
- spleen
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - DNA-binding transcription factor activity
- metal ion binding
- methylated histone binding
- protein binding
- chromatin binding
- nucleosome binding
- sequence-specific DNA binding
| Cellular component | - cytoplasm
- site of double-strand break
- ESC/E(Z) complex
- nucleoplasm
- microtubule organizing center
- cytoskeleton
- nucleus
- centrosome
| Biological process | - negative regulation of histone H3-K27 methylation
- regulation of transcription, DNA-templated
- transcription, DNA-templated
- cellular response to DNA damage stimulus
- regulation of histone methylation
- negative regulation of gene expression, epigenetic
- positive regulation of histone H3-K27 methylation
- chromatin organization
- positive regulation of transcription, DNA-templated
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000112511 ENSG00000225553 ENSG00000239756 |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 6: 33.41 – 33.42 Mb | Chr 17: 27.15 – 27.16 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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