ZBTB40

Protein-coding gene in the species Homo sapiens
ZBTB40
Identifiers
AliasesZBTB40, ZNF923, zinc finger and BTB domain containing 40
External IDsOMIM: 612106; MGI: 2682254; HomoloGene: 8912; GeneCards: ZBTB40; OMA:ZBTB40 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for ZBTB40
Genomic location for ZBTB40
Band1p36.12Start22,428,838 bp[1]
End22,531,157 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for ZBTB40
Genomic location for ZBTB40
Band4|4 D3Start136,707,043 bp[2]
End136,776,112 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tibia

  • right coronary artery

  • sperm

  • endothelial cell

  • sural nerve

  • inferior olivary nucleus

  • cardia

  • gastric mucosa

  • saphenous vein

  • left adrenal gland
Top expressed in
  • otolith organ

  • utricle

  • ascending aorta

  • aortic valve

  • urethra

  • female urethra

  • spermatocyte

  • Paneth cell

  • male urethra

  • superior cervical ganglion
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • DNA binding
  • metal ion binding
  • nucleic acid binding
  • molecular function
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
  • extracellular region
Biological process
  • bone mineralization
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • cellular response to DNA damage stimulus
  • regulation of transcription by RNA polymerase II
  • negative regulation of endopeptidase activity
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

9923

230848

Ensembl

ENSG00000184677

ENSMUSG00000060862

UniProt

Q9NUA8
Q1RMZ5

Q6PCS8

RefSeq (mRNA)

NM_001083621
NM_014870
NM_001330398

NM_198248

RefSeq (protein)

NP_001077090
NP_001317327
NP_055685
NP_001077090.1
NP_055685.3

NP_937891

Location (UCSC)Chr 1: 22.43 – 22.53 MbChr 4: 136.71 – 136.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger and BTB domain-containing protein 40 is a protein that in humans is encoded by the ZBTB40 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000184677 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060862 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZBTB40 zinc finger and BTB domain containing 40".

Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones" (PDF). DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
  • Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.

External links


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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies